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What is Sildenafil With Duloxetine?
The combination of Sildenafil and duloxetine is a powerful medicine to address the issue of male impotency. It is prescribed to treat erectile dysfunction and premature ejaculation. It is sometimes prescribed for pulmonary arterial hypertension.
Class and Mechanism of Action
Sildenafil contains Sildenafil as an active ingredient. It is a phosphodiesterase type 5 inhibitor. Its PDE5 inhibiting action releases more of cGMP in the Corpus Cavernosum of a penis. An increased level of cGMP relaxes the smooth muscles and improves blood flow. Duloxetine is a serotonin-norepinephrine reuptake inhibitor. It inhibits serotonin reuptake, thereby increasing its amount exponentially in the blood. It’s action at the postsynaptic cleft increases thereby preventing premature ejaculation.
Looking after your drug
Store it in a cool and dry place away from the reach of children and pets.
How to take Sildenafil With Duloxetine?
Take it orally with a light meal at least 30 minutes prior to a sexual activity. The effect may last up to many hours.
The usual recommended dose is one pill a day. However, consult your doctor for your dose.
Consult your doctor right away.
If it is time for your next dose, then skip the missed dose or else take it as soon as you remember. Do not double dose.
Warnings and Precautions
Inform your doctor about other disease conditions you are suffering from and the medications taking. Do not take it with medicines containing nitrates. Do not consume alcohol. Seek immediate medical help if your erection lasts for more than 4 hours.
Possible Side Effects
- Nasal discharge and stuffiness
- Vision disturbances (blurred vision, photophobia, blue-tinted vision)
When should Sildenafil With Duloxetine not be used?
Heart disease, blood disorders, glaucoma, Kidney & liver diseases and allergy to the medicine
How long should you take Sildenafil With Duloxetine?
As long as prescribed.