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Ketoconazole is an antifungal drug used to treat fungal infections of the skin, fungal infection of the foot and hand. It is also used for the prevention and treatment of fungal infection of the scalp including dandruff and yeast infections of the skin.
How it works
Ketoconazole acts mainly by preventing the growth of fungi. It prevents yeasts and fungi from reproducing and from making their protective outer cell wall.
Common side effects
Decreased platelets, Bleeding, Inability to achieve an erection, Blockade of synthesis of hormones from adrenal glands, Itching of skin, Indigestion, Ketoconazole cream, and shampoo: skin burning sensation, Dryness, Folliculitis, Skin rash, Numbness, Vomiting, Burning of skin).oral ketoconazole:nausea, Increased tears, Abdominal pain diarrhea, Redness of skin, Discomfort, Hair loss., Raised pressure in fluid surrounding the brain and spinal cord, Skin exfoliation sticky skin, And application site bleeding, Irritation, Hypersensitivity reactions, Dizziness, Intolerance to sunlight, Liver damage, Pricking, Tingling, Hair loss, Enlargement of breasts in men, Drowsiness and rash, Inflammation, Headache, Decreased sperm count, Menstrual disorders.
If you are taking an antacid to take it 1 hour before or 2 hours after taking ketoconazole.
Limit alcohol intake. Consuming alcohol while taking ketoconazole increases the risk of liver damage.
Do not continue ketoconazole and consult your doctor:
- If you experience an allergic reaction, swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing.
- If you experience severe irritation or reddening of the skin where ketoconazole is applied or other signs of allergy during the first few days of treatment.
- If you experience peeling or blistering of the skin.
- Dandruff shampoo may be irritating to eyes and contact with this area should be avoided.
- Consult your doctor if your symptoms have not been relieved within one week of taking ketoconazole.
Frequently asked questions
Q. Is ketoconazole/Ketoconazole shampoo safe?
Yes, all medicines (products) containing ketoconazole are safe at the recommended doses or when used at the recommended frequency.
Q. Is ketoconazole/ ketoconazole cream an antibiotic?
No, ketoconazole is not an antibiotic as it does not kill bacteria. It belongs to the triazole class of antifungal agents.
Q. Is ketoconazole/ ketoconazole OTC?
No, ketoconazole products are under schedule H and are available on producing a prescription from your doctor.
Q. What is ketoconazole/ketoconazole cream/Phytoral ointment used for?
Ketoconazole containing products such as creams and Phytoral ointments are used to treat fungal infections of the skin such as tinea corporis (ringworm), tinea cruris (fungal infections of the groin or buttocks), tinea pedis (fungal infection of the foot [athlete’s foot]), tinea manus (fungal infection of the hand).
Q. Can I take ketoconazole with amoxicillin, ibuprofen, Tylenol (paracetamol), omeprazole, Benadryl (cough preparation)?
There are no known serious drug interactions between ketoconazole and drugs such as ibuprofen, Tylenol (paracetamol), Benadryl (cough preparation). It may interact with amoxicillin and omeprazole, where the absorption of ketoconazole may be reduced. Consult your doctor about all medications currently taken before starting and while on ketoconazole.
Q. Can ketoconazole cause hair loss?
Yes, ketoconazole may rarely cause some hair loss.
Q. Can ketoconazole prevent hair loss?
No, ketoconazole does not prevent hair loss. In fact, it may rarely cause hair loss.
Q. Can ketoconazole cause dry skin?
Yes, dry skin at the site of the application is a common side effect of ketoconazole.
Q. Can ketoconazole be used for conditions such as ringworms and psoriasis?
Yes, ketoconazole is commonly used to treat fungal infections of the skin such as ringworms. Psoriasis is not a fungal skin infection and use of ketoconazole is not warranted to treat this condition.
Q. Is ketoconazole/ ketoconazole cream a steroid?
No, ketoconazole is not a steroid. It belongs to the triazole class of antifungal agents.
Q. Is ketoconazole safe in pregnancy?
Ketoconazole in the form of cream and shampoo may be used in pregnant women if the benefit outweighs the risk. Ketoconazole tablets are preferably not to be used in pregnancy. Patients should follow the advice of the doctor regarding its use.
Q. Is ketoconazole safe in breastfeeding?
No, ketoconazole tablet, cream or shampoo is contraindicated in breastfeeding.
Q. Can I ketoconazole at bedtime?
Ketoconazole can be taken at any time during the day.
Q. Can ketoconazole be taken for yeast infections?
Yes, ketoconazole is prescribed for yeast infection. Patients should follow the advice of the doctor regarding its use.
Q. Does ketoconazole block Dihydrotestosterone (DHT)?
Ketoconazole has the ability to block the synthesis of all steroids produced by the adrenal gland, including the male sex hormone dihydrotestosterone. Testosterone synthesis from the testes is also blocked.
Q. Does ketoconazole expire?
Yes, medicines containing ketoconazole have an expiry date. Read the information given on the package for accurate expiry date.