What is Daclahep?

Daclahep (Daclatasvir) is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body. Daclahep is used to treat genotype 1 and genotype 3 chronichepatitis C in adults with or without cirrhosis. Daclahepis given together with another drug called Sovaldi (sofosbuvir). Daclahep tablets contain the active ingredient daclatasvir, which is a type of medicine called an antiviral. It is used in combination with other medicines to treat chronic hepatitis C. Hepatitis C is a virus that infects the liver and leads to liver damage. Once the virus is inside the liver cells it multiplies. Part of this process involves the virus making copies of its genetic material (RNA and DNA).

How does Daclahep work?

Daclatasvir works by blocking the action of an enzyme called 5A (NS5A) in the hepatitis C virus, which is essential for the virus to multiply. This stops the hepatitis C virus from multiplying, which lowers the amount of hepatitis C virus in the liver. This helps to reduce liver damage and improves liver function.

Daclatasvir must be used in combination with other medicines that attack the hepatitis C virus in different ways. If daclatasvir is used on its own there is a high chance that the hepatitis C virus will become resistant to it.

What is Daclahep used for?

Treating chronic hepatitis C infections (genotype 1, 3 and 4) in adults with uncomplicated liver disease whose liver is still functioning correctly (compensated liver disease). Daclahep may be used in people who have not yet received treatment for their hepatitis C, or for people whose disease has not improved with previous treatment. Daclahep may be used in combination with sofosbuvir (Sovaldi), either with or without ribavirin (Rebetol), or with ribavirin plus peginterferon alfa (ViraferonPeg or Pegasys).

Important information

Serious drug interactions can occur when certain medicines are used together with daclatasvir. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

Before taking this medicine

You should not use Daclahep if you are allergic to daclatasvir. If you take daclatasvir with sofosbuvir, there may be other reasons you should not take this combination treatment. Tell your doctor about all your medical conditions. Some medicines can interact with Daclahep and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs: rifampin, carbamazepine, phenytoin.

To make sure Daclahep is safe for you, tell your doctor if you have:

• liver problems other than hepatitis C;
• heart disease;
• if you also use amiodarone (a heart rhythm medicine); or
• if you have received a liver transplant.

It is not known whether Daclahep will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether daclatasvir passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Daclahep is not approved for use by anyone younger than 18 years old.

How should I take Daclahep?

Daclahep is usually taken for 12 weeks. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Daclahep must be given in combination with sofosbuvir and it should not be used alone. You may take Daclahep with or without food.

Hepatitis C is often treated with a combination of drugs. Use all medications as directed by your doctor. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Do not stop using any of your hepatitis C medicines without your doctor’s advice. Do not change your doses or medication schedule without first asking your doctor. Every person with chronic hepatitis C should remain under the care of a doctor. You will need frequent blood tests to check your liver function while using Daclahep.

Store at room temperature away from moisture and heat.

Daclahep dosing information

Usual Adult Dose for Chronic Hepatitis C:
60 mg orally once a day for 12 weeks
Comments:
-Sustained virologic response rates reduced in HCV genotype 3-infected patients with cirrhosis using this drug with sofosbuvir for 12 weeks; optimal duration of therapy has not been established for patients with cirrhosis.
-The manufacturer product information for sofosbuvir should be consulted.

Use: In combination with sofosbuvir, for the treatment of patients with chronic HCV genotype 3 infection

What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call to your doctor.

What should I avoid while taking Daclahep?

Taking Daclahep will not prevent you from passing hepatitis C to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HCV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Daclahep side effects

Get emergency medical help if you have signs of an allergic reaction to Daclahep: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

FAQ

What is the Generic Name for the trade name drug “Daklinza”?

Daclatasvir mepesuccinate is Generic Name for the trade name drug Daclahep.

What is the Manufacturer Name of Daclahep ?

Daclahep is manufactured by Natco Pharma, India

Is Daclahep approved by FDA?

Yes, Daclahep is approved by FDA.

What is the dosage and form of Daclahep is available?

Daclahep is available 30 mg and 60 mg film-coated tablets

What are the indications and usage of Daclahep?

Daclahep is a anti body-drug conjugate indicated for: The treatment of The treat adults with hepatitis C. after failure of autologous stem cell transplant (ASCT) or after failure of at least two prior multi-agent chemotherapy regimens in patients who are not ASCT candidates and The treatment of patients with systemic anaplastic large cell lymphoma after failure of at least one prior multi-agent chemotherapy regimen. These indications are based on response rate. There are no data available demonstrating improvement in patient reported outcomes or survival with Daclahep.

SOURCING:

SafeGenericPharmacy is able to source Daclahep Brentuximab Vedotin (Cancer Treatment Medicines) from across the globe, and has ability to supply. Indian Pharma offers its customers worldwide access to the best available treatment.

DELIVERY:

SafeGenericPharmacy is able to dispense any valid prescription in shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to Patientbs address only from India.

Is Daclahep available in India?

Daclahep is a pharmaceutical drug that legally requires a medical prescription to be dispensed. SafeGenericPharmacy facilitates Export of cancer medicines on the named patient supply. SafeGenericPharmacy is facilitator providing input.

• On availability in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc.)
• Medicine Price.
• Finding Genuine and reliable source from Europe, USA and Australia
• Ensuring 100% transparency.

Daclahep can be made available Europe, USA and Australia, SafeGenericPharmacy can facilitate the supply of Daclahep(prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable). Please email us for bulk discount, We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

How order will be confirmed?

The order will be confirmed only after the receipt of

• Valid prescription of Oncologist
• Import permit if applicable

Where can I Buy Daclahep (Daclatasvir Tablets)?

SafeGenericPharmacy connects buyer with the supplier who can ship Daclahep (Daclatasvir Tablets) (Cancer Treatment Medicines) to any country of the world as per the buyer’s requirement and Government regulations of the country. Daclahep is Marketed By Hetero Drugs. SafeGenericPharmacy provides options of choosing exporter and supplier of Cancer treatment Medicines We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

Daclahep price online

this can be the opportunity to get the best prices of your hep c treatment. Before contacting us please take into account that the medicine has to be prescribed by a doctor, and you must provide the prescription to us and we will verify it with your doctor. We are able to deliver the Daclahep to almost every country in the world, directly to your doctor’s office or through a net of allied pharmacies.

If you want more information about Daclahep,to get more information about the HCV visit our Hep C Blog

To get your best Daclahep quote visit our online pharmacy.

Generic components: Daclatasvir

Usually prescribed to treat chronic hep c infection

Original Brand Manufactured by Bristol-Myers Squibb 

Daclahep Launch

On 17th December 2105 Natco Pharma got approval for generic Daclatasvir Dihydrochloride (“Daclatasvir”) tablets, Daclahep 30mg and Daclahep 60mg, from Drugs Controller General (India). Daclatasvir (Daclahep) is the first-in-class NS5A inhibitor used in combination with Sofosbuvir for the treatment of patients with chronic hepatitis C virus (HCV) genotype 3 infection. Compared to other treatment options, this combination not only increases the cure rate, but is also regarded as a valuable treatment option in some of the difficult-to-treat HCV patient subsets.

U.S. Food and Drug Administration approved Daclahep (Daclatasvir) for use with sofosbuvir to treat hepatitis C virus (HCV) genotype 3 infections on July 24, 2015 . Daclahep (Daclatasvir) is the first drug that has demonstrated safety and efficacy to treat genotype 3 HCV infections without the need for co-administration of interferon or ribavirin, two FDA-approved drugs also used to treat HCV infection.