Buy Cytogard 20mg (Trimetazidine) Online

Uses

Trimetazidine is used for symptomatic treatment of stable angina (chest pain) as an additional therapy to other frontline medicines.

How it works

Trimetazidine belongs to a metabolic modulators class of medicines also known as pFOX inhibitors (partial fatty-acid-oxidation inhibitor). In myocardium (muscles of the heart), trimetazidine partially inhibits the metabolic process (?-oxidation) of fatty acid that requires more oxygen consumption) by blocking a specific enzyme (long-chain 3-ketoacyl-CoA thiolase) and thereby triggering glucose oxidation that requires less oxygen consumption. Angina is caused due to decreased oxygen supply to the cells of the heart as a result of reduced blood flow. Trimetazidine thus triggers processes that increase cellular energy (potentiation of glucose oxidation), thereby acts by preserving the myocardial high-energy and makes oxygen available for the cells of the heart. THERAPEUTIC INDICATIONS This drug is recommended in:

• Preventive treatment for episodes of angina pectoris (Chronic stable angina).
• Adjuvant symptomatic treatment for vertigo and tinnitus (noises detected by the ear whistling, buzzing, which do not correspond to any exterior sounds).
• Adjuvant treatment of visual disorders of a circulatory origin.

CONTRAINDICATIONSDo not take Vastarel MR if you are allergic to any of the constituents.This drug is generally not recommended during breastfeedingSPECIAL WARNINGS AND PRECAUTIONSThis drug is not a curative treatment for angina attacks, nor an initial treatment for unstable angina pectoris. It is not a treatment for myocardial infarction. In the event of an angina attack, inform your doctor. Tests may be required and your treatment may possibly be modified.SIDE EFFECTSAs with all drugs, Vastarel MR is likely to have undesirable effects:

• Rare cases of gastrointestinal disorders (nausea, vomiting)
• if you notice any undesirable effects, which have not been mentioned here, you should inform your doctor or pharmacist.

PREGNANCY AND BREASTFEEDINGPregnancyIt is preferable not to take this medicine during pregnancy if you discover that you are pregnant whilst taking this medicine, consult your doctor as he alone can judge the necessity of continuing your treatmentBreastfeedingIn the absence of data on excretion in breast milk, breastfeeding is not recommended during treatment. Ask your doctor or pharmacist’s advice before taking any medicine.DOSAGE AND METHOD OF ADMINISTRATIONOral route.The usual dosage is 1 tablet in the morning and evening. Tablets should be swallowed with a glass of water at mealtimes. If you think that the effect of Vastarel MR is too strong or too weak, talk to your doctor or pharmacist.OVERDOSAGEConsult a doctor or a pharmacist immediately.WHAT TO DO IN CASE ONE OR SEVERAL DOSES HAVE BEEN MISSEDResume treatment normally. Do not take a double dose to compensate for the single-dose that you forgot to take.STORAGE CONDITIONSKeep out of the reach and sight of children.Do not use after the expiry date indicated on the box.

Expert advice

• Trimetazidine may make you feel dizzy and drowsy which may affect your ability to drive or use machinery. Trimetazidine should be discontinued if there is no treatment response after a 3-month treatment benefit assessment. Inform your doctor before you start trimetazidine:
• If you are currently taking any other medicine
• If you are pregnant, breastfeeding or planning to get pregnant
• Inform your doctor immediately if you experience trembling, rigid posture, slow movements and shuffling, unbalanced walk, especially in elderly patients.
• Caution should be exercised as falls may occur following a drop in blood pressure or loss of balance. Inform your doctor if you experience signs of an angina attack (sensation of pressure, squeezing, or pain in chest) while on trimetazidine.
• Patients with moderate kidney problems and patients above 75 years must exercise caution for increased risk to side effects while on trimetazidine.

Frequently asked questions

Trimetazidine

Q. Is trimetazidine available in the USA?No, trimetazidine is not available in USA.Q. Is trimetazidine available in Canada?No, trimetazidine is not available in Canada.Q. What is trimetazidine/ trimetazidine dihydrochloride used for?Trimetazidine is used in the treatment of angina pectoris (sensation of pressure, squeezing, or pain in the chest due to insufficient blood supply to the muscles of the heart) as an additional therapy to other frontline medicines. It may also be used in patients who do not respond well to other anti-anginal medicines.Q. How does trimetazidine work?Trimetazidine belongs to a metabolic modulators class of medicines also known as pFOX inhibitors (partial fatty-acid-oxidation inhibitor). In myocardium (muscles of the heart), trimetazidine partially inhibits the metabolic process (?-oxidation) of fatty acid that requires more oxygen consumption) by blocking a specific enzyme (long-chain 3-ketoacyl-CoA thiolase) and thereby triggering glucose oxidation that requires less oxygen consumption. Angina is caused due to decreased oxygen supply to the cells of the heart as a result of reduced blood flow. Trimetazidine thus triggers processes that increase cellular energy (potentiation of glucose oxidation), thereby acts by preserving the myocardial high-energy and makes oxygen available for the cells of the heart.