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UsesAprepitant is used in adults in combination with other medicines to prevent nausea and vomiting caused by cancer chemotherapy or after a surgery.
How it worksAprepitant is an antiemetic and belongs to a group of medicines called neurokinin 1 (NK1) receptor antagonists. It works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.
Common side effectsindigestion, Constipation, increased amount of liver enzymes in blood, stomach upset, tiredness, heart burn, hair loss., loss of appetite, diarrhea, dizziness, hiccups, headache, weakness.
- Aprepitant can only prevent nausea and vomiting and is not used for its treatment. Do not start aprepitant if you are already having nausea or vomiting.
- If you have liver disease, you may be monitored with liver function test regularly, as it may affect the breakdown of this medicine in your body.
- You are advised to use another or additional non-hormonal form of birth control method during and after up to 2 months of using aprepitant, as certain hormonal birth control [e.g. birth control pills, skin patches, implants, and certain intrauterine devices (IUDs)] may not work adequately when taken along with aprepitant.
- Do not drive or use machinery while taking Aprepitant as it may make you feel dizzy and sleepy.