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This tablet is utilized for the treatment of average to severe dementia (confusion) related to Alzheimer’s disease. It cannot treat the disease, but it can help the affected person by improving his awareness, memory, and ability to perform different types of routinely functions. It works on the substance glutamate in our brain by acting as an NMDA receptor antagonist, which may help in the reduction of the symptoms related to Alzheimer’s disease. Admenta medicine contains Memantine as an active ingredient.
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Memantine is used in adult patients to treat moderate to severe Alzheimer’s disease (a disorder that causes mental confusion and forgetfulness).
How it works
Memantine belongs to the group of medicines called psychoanalytic. It acts by modulating the effects of increased levels of the chemical substance in the brain called glutamate and thus decreasing abnormal activity in the brain.
What is Memantine?
Memantine is an Alzheimerâ€™s Disease medication that reduces the actions of chemicals in the brain that may act as factors in bringing about the symptoms of this disease. Memantine is prescribed for the treatment of moderate to severe dementia of the Alzheimerâ€™s type. Memantine is sold under various trade names, some of which are Admenta (Sun Pharma). This medication may also be given for conditions not mentioned here.
Important Information about Memantine
Do not take Memantine (Admenta) if you are allergic to it. Notify your doctor in advance if you are allergic to any other drugs or if you have any of the following conditions: epilepsy or seizure disorders, cataract, liver or kidney disease, or a bladder or kidney infection. Having any of these conditions may require dose adjustments from the normal dosage of this medication. Memantine can impact your thinking and reflexes. Be extra careful when you drive or do activities that require a high degree of mental awareness. Memantine is an FDA pregnancy category B drug. It is not expected to be harmful to an unborn baby when taken during pregnancy. It is not known whether Memantine can pass into breast milk and harm a nursing baby. You must notify your doctor beforehand if you are pregnant, planning to become pregnant or breastfeeding.
Before taking Memantine
Before taking Memantine, take care of all the precautions and points mentioned above and discuss them with your doctor. Clarify any doubts you may have regarding this medication.
How should I take Memantine?
Take Memantine (Admenta) exactly as prescribed by your doctor. All medications come with a patient leaflet with complete instructions and details. Refer to it for any doubts. Do not alter the course of the medication in any way (do not take more or less than the prescribed dosage). Also do not take it after the period for which the medication was prescribed is over. You may take Memantine with or without food. Take it with a full glass of water. Always store Memantine medication in a cool and dry place.
What if I forgot to take a dose of Memantine?
Do not miss a single dose of Memantine. However, if you miss a dose, take it as soon as you remember it. Do not take the missed dose if the time to take the next dose is almost up. Instead, continue with the original schedule. Never take multiple doses closer to each other.
What to do in case of an Overdose?
In case of an overdose of Memantine, get emergency medical attention or call the Doctor immediately. Overdose may cause restlessness, drowsiness, unusual behavior, hallucinations, lightheadedness, or fainting.
Things and Activities to avoid while using Memantine
Follow any diet and activity restrictions advised by your doctor strictly, especially with regards to any activity that requires a high level of mental alertness. Memantine can impact your thinking ability and reflexes. This may make activities like driving daunting and tough, so be extra careful.
Memantine Side Effects
Some common and less serious side effects of Memantine are dizziness, hallucinations, confusion, loss of coordination, seizures, fainting, joint pain, anxiety, swelling in hands or feet, constipation, and headache. If any of these side effects continue for a long time and deteriorate, seek medical attention right away. Memantine rarely causes any serious side effects but if you experience them, stop using the medication and get emergency medical attention. The side effects mentioned thus are not all the possible ones, there may be others.
Memantine Dosing Information
Memantine dosage will be decided by your doctor after properly examining you. However, the normal dosage is 5 mg orally once daily initially, then incremented by 5 mg per week. The maintenance dosage is 5mg once daily up to 10 mg twice daily. The maximum daily dose of Memantine should not exceed 20 mg.
Interaction with other drugs
Some drugs can interact with Memantine. Let your doctor know in advance if you are using any of these medications already: cimetidine, nicotine, ranitidine, quinidine, sodium bicarbonate, antiviral drugs such as rimantadine or amantadine, cold or cough medicines that contain dextromethorphan, a diuretic which such as hydrochlorothiazide or triamterene, drugs to treat glaucoma such as acetazolamide or dichlorphenamide, or oral diabetes medications that contain metformin. These drugs are not all the possible ones that can interact with Memantine. There may be others. Let your doctor know about all other drugs which you may be using. Never start a new medication without proper medical screening and advice.
- Do not start or continue the memantine if you are allergic to memantine or any other ingredients in the medicine.
- Do not take memantine if you have a history of fits (convulsions or seizures); heart disorders.
- Avoid taking memantine if you are pregnant or breastfeeding.
- Do not take memantine if you have recently changed or intend to change your diet substantially (e.g. from a normal diet to a strict vegetarian diet).
- Do not take memantine if you are suffering from states of renal tubular acidosis (an excess of acid-forming substances in the blood due to poor kidney function); severe infections of the urinary tract.
Frequently asked questions
Q. Is memantine available in the US/Canada?
Yes, memantine is available in the US/Canada.
Q. Is memantine a cholinesterase inhibitor/antipsychotic drug/anticholinergic?
Memantine belongs to the group of medicines called psychoanalytic. It is not a cholinesterase inhibitor/antipsychotic drug/anticholinergic.
Q. Is memantine a controlled substance?
No, memantine is not a controlled substance.
Q. Does memantine increase acetylcholine?
No, it does not increase acetylcholine.
Q. Does memantine cause drowsiness/make you sleepy?
Yes, memantine cause drowsiness or sleepiness. Always consult your doctor if the symptoms are severe.
Q. Does memantine come in liquid form?
Yes, memantine is available in liquid form as an oral solution.
Q. Does memantine increase dopamine?
Concurrent use of memantine and dopamine may increase the dopamine level in the blood. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does memantine help vascular dementia?
Memantine may help in vascular dementia. The patient should follow the advice of the doctor regarding its use.
Q. How does memantine work in the body?
It works by modulating the effects of increased levels of the chemical substance in the brain called glutamate and thus decreasing abnormal activity in the brain.